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Two molecules, GHK and securinine topped the list and were selected out of 1,309 bioactive molecules as the best agents capable to reverse expression of 54 gene sets overexpressed in malignant invasive metastatic colon cancer, which included node molecules YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2, involved in regulation of multiple biochemical pathways [ 27 ]

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After administration, GC levels increase and reach maximum values after a species- and matrix-specific time-lag

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Br J Pharmacol 2022, 179(4): 659-676

Off-target effects via inhibition of the related SGLT1 transport protein may also mediate reductions in oxidative stress seen in cardiac tissue [155]