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important nuance with the "glp-1 causes lean mass loss" debate: dexa scans are the tools we most commonly use to assess body composition, and they cannot distinguish actual muscle tissue loss from intramuscular fat loss (fat that surrounds the muscle)

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One study compared them directly and found that gastric emptying half-time was delayed by 52 minutes with lixisenatide (short-acting) but only 25 minutes with liraglutide (long-acting) [2]

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This, in turn, is leading to a rise in their adoption rates

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