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Figure 1 FAERS is a publicly available and anonymous database

Hypermelanosis of basilar keratinocytes can be seen in a number of other lesions, such as Becker's nevus (hyperpigmentation associated with hypertrichosis and smooth muscle hamartoma) ( Fig

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Histological examination was carried out in all cases and it revealed interface dermatitis with vacuolar degeneration of the basal cells, a dense lympho-mononuclear perivascular and perifollicular infiltrate with abundant melanophages in the papillary and high reticular dermis