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When safety of the study participants and technological developments allow, so called biomarkers can be used to collect PD data to understand if the drug reaches the target, binds to the target and exerts its expected pharmacological activity within the dose range tested
Medical oversight and appropriate dosing are essential
This applies regardless of your experience with other peptide products
Biomarkers of Alzheimer's include abnormal levels of betaamyloid and tau in blood and cerebrospinal fluid (CSF, the fluid surrounding the brain), the accumulation of betaamyloid and abnormal tau as seen on positron emission tomography (PET), decreased glucose metabolism as seen using PET and a compound called [ 18 F]fluorodeoxyglucose, brain atrophy as determined by structural magnetic resonance imaging (sMRI), and increased levels of the neurofilament light chain protein in CSF or blood, among others
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