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In addition, a single dose administration of 3 g/kg of PGN into the stomachs of baboons resulted in 36 mg/kg being excreted in the urine over 24 hour period, again indicating intestinal absorption of PGN, albeit in very small quantities (Beattie et al

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Pregnancy, uncontrolled thyroid disease, and active pancreatitis also require careful provider assessment

These medications may be appropriate for some patients with obesity, overweight with related medical conditions, or diabetes, but they still need to be considered in the context of the patient in front of you