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Key Distinction: Semax is not simply anti-anxiety Selank but stronger. It is a different tool, aimed more at cognitive activation and neuroprotection

neural systems rewrite themselves during observation incomplete state observability (glia, neuromodulators, intracellular states) multiple incompatible timescales (ms days) immature and simplified systems exaggerate drift and stochasticity So what do we do instead

OPs in T cells, microglia/macrophages, astrocytes, oligodendrocytes, and neuron in the CNS of MS patients reduces Nrf2 and increases NF-kB, and may promote the release of inflammatory cytokines

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Epidemiologically, full truncal vagotomy (cutting vagus connections to gut) has been associated with lower PD incidence, hinting that in some patients the gut-to-brain route is critical [33]