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Our data demonstrate that acetaminophen accumulates in Drosophila , resulting in the generation of ROS in the fat body (an organ analogous to the mammalian liver 21 ), a rapid depletion of systemic glutathione, and subsequent mortality

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Stroke remains one of the leading causes of death and long-term disability worldwide, accounting for nearly 18% of cardiovascular disease-related deaths in the U.S

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By using the specific activity of purified recombinant GSTP1, the GSTP1 protein concentration in transfected cells was estimated at 4051 g/mg cytosolic protein

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[7] The synthesis of GSH occurs exclusively in the cytosol, from where it is transported to different subcellular compartments, such as the endoplasmic reticulum (ER), Golgi apparatus, mitochondria and the nuclear matrix

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GLP-RT peptide supplied by New England Biologics is intended strictly for research and development use only

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