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PMID 12814619

Antioxidants & Redox Signaling , 15 (1), 3947

Deficiencies in B12 can directly lead to nerve damage and worsen symptoms of diabetic neuropathy.65 While most people can get adequate B12 through diet (meat, fish, dairy, fortified cereals), certain medications including metformin and proton pump inhibitors can impair absorption and raise the risk of deficiency

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Noseda R., Burstein R

Furthermore, this not only contributes to disease, but also contributes to skin sagging, discolouration, dryness, and aging