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Further oxidative damage, to DNA specifically, was investigated via plasma 8-OHdG, one of the best measures of the mutagenic consequences of oxidative stress (Reference Mecocci, Fan and Fulle31)

The HDC gene is located on chromosome 15q21.2 and is composed of 14 exons that generate two alternatively spliced mRNAs encoding two distinct isoforms of the enzyme

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CARNITOR (levocarnitine) Injection is available in 1 g per 5 mL single dose vials packaged 5 vials per carton (NDC 54482-147-01)

Authors' contributions HZ and ZJ wrote and reviewed the manuscript

Recent trials have explored other precursors beyond NR