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So that was the problem that then came up

Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimotos Thyroiditis

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This Temporal pattern-based analysis showed 660 differentially expressed proteins during the early phase (391 upregulated, 269 downregulated in Day 15), 543 during the mid phase (273 upregulated, 270 downregulated in Day 30), and 688 during the late phase (292 upregulated, 396 downregulated in Day 45) (Supplementary Table 1)

Instead, we propose to examine how such factors work and to evaluate the reparative tools generously provided by nature. We used two approaches to address these objectives